Tyrannion (Ancient Greek: Τυραννίων) may refer to:
Tyrannion of Amisus (fl. 1st century), Greek grammarian
Tyrannion of Antioch (died c. 308), Patriarch of Antioch
Tyrannion of Tyre (died 311), Bishop of Tyre
Tyrannion the Younger, a Greek sophist and pupil of Tyrannion of Amisus
Tyrannion of Messenia, a Greek philosopher